Thursday, December 16, 2021

Herrera presents renal pathology research at international meeting

Guillermo Herrera, M.D., professor and chair of pathology at the USA College of Medicine, recently presented at a symposium on AL-amyloidosis in the kidney for the American Society of Nephrology Kidney Week 2021. More than 10,000 nephrologists, pathologists and basic science researchers attended the virtual meeting.

He presented on “Fibril Generation in Amyloidosis: Potential for Therapeutic Interruption.” In the session he discussed new opportunities for therapeutically preventing, interrupting and reversing amyloid deposition in the kidney and other organs. 

Other members of the research team responsible for the findings included Jiamin Teng, M.D., Ph.D., associate professor of pathology; Elba Turbat-Herrera, M.D., professor of pathology; Luis del Pozo-Yauner, M.D., Ph.D., assistant professor of pathology; and Chun Zeng, Ph.D., research associate in pathology.

Herrera earned his medical degree from the University of Puerto Rico School of Medicine in San Juan. He completed his residency training in anatomic and clinical pathology at Brooke Army Medical Center in San Antonio, Texas. He is certified by the American Board of Pathology in anatomic and clinical pathology and cytopathology. 

More than 75 children assisted by medical students during Saturday health camp

Medical students, residents and attending physicians volunteer at the pediatric health camp.
Nearly 80 children took part in a free pediatric health camp on Saturday, Dec. 4, hosted by the USA Health Pediatric Residency Diversity Coalition at Cody Road Seventh-day Adventist Church.

USA College of Medicine students, along with resident physicians, attendings and faculty members, took part in the event aimed at Spanish-speaking members of the community.

“The medical students were a key component of the community outreach,” said Renee Roca, M.D., an assistant professor of pediatrics at the USA College of Medicine and a hospitalist at Children’s & Women’s Hospital.

More than 20 medical students volunteered their time during the Saturday initiative to help with everything from anthropometric screening, vision screening, developmental screenings, health education including dental hygiene, car seat safety, water safety, safe sleep and vaccinations.

The event was held in partnership with Ascension Providence Guadalupe Center and the USA Regional Autism Network (RAN).

View more photos from the event on Flickr

Medical student completes prestigious rheumatology preceptorship

Emily Polhill, a second-year medical student at the USA College of Medicine, earned a sought-after medical student preceptorship from the Rheumatology Research Foundation. She recently was recognized as one of the recipients at the American College of Rheumatology national meeting, held virtually in early November. 

Awarded to only 30 medical and graduate students each year, the $4,000 grant provided financial support for Polhill to complete a preceptorship in rheumatology. Preceptorships encourage students to learn more about rheumatology and pursue careers in the field by supporting a one-on-one, real-world learning experience.  

A native of Birmingham, Polhill worked with pediatric rheumatologist Melissa Mannion, M.D., of the University of Alabama at Birmingham. During her preceptorship, she studied qualitative analysis and coding of interviews for pediatric rheumatology groups. The goal of her research was to understand the differences in institutional context that may influence the quality of care delivered to children with juvenile idiopathic arthritis.

This past summer, Polhill shadowed Mannion at Camp MASH, or Make Arthritis Stop Hurting, a camp for children ages 7 to 17 with a form of juvenile arthritis or a related auto-immune disease. Mannion encouraged Polhill to apply for the preceptorship award through the Rheumatology Research Foundation.

A graduate of Brigham Young University, Polhill said she is grateful for the experience and knowledge she gained through the preceptorship.

Cancer researchers at MCI receive BCRFA funding

Three cancer researchers at the USA Health Mitchell Cancer Institute have received grants from the Breast Cancer Research Foundation of Alabama as part of the organization’s $1.2 million investment in state-based research in 2021.

The recipients of the three awards, totaling almost $110,000, include Robert W. Sobol, Ph.D., professor of pharmacology; Lyudmila Rachek, Ph.D., assistant professor of pharmacology; and Santanu Dasgupta, Ph.D., assistant professor of pathology at the USA College of Medicine.

BCRFA grants often act as seed funding for developing studies, allowing scientists to generate data needed to obtain major national funding.

Sobol will use a $50,000 BCRFA grant to expand his study of a new treatment combination targeting breast cancer that is resistant to therapy. The treatment combines a PARG inhibitor, a compound that keeps the enzyme PARG from enabling tumor cells to replicate, with small molecules to regulate cellular NAD+ levels, developed by Marie E. Migaud, Ph.D. Sobol will test the combination treatment and the PARG inhibitor alone in breast cancer cell lines and normal breast cells.

“Our goal will be to expand our analysis to a large panel of breast cancer and breast normal cells, eventually allowing strategic targeting to breast cancers with this combination treatment,” he said.

Rachek and her team will use a $35,000 grant for a one-year project to elucidate the protective mechanisms of mitochondrial delivery of TAT-hOGG1 in breast cancer progression. For this, they will perform gene expression analysis in mouse breast cancer models with mitochondrial-targeted TAT-hOGG1 using RNA sequencing.

“This study has important clinical and translational significance and will provide the basis for new unconventional therapeutic approaches for treating breast cancer,” Rachek said. “This project is particularly timely given the lack of available effective therapies and prognosis for patients with advanced breast cancer. We are very grateful to the BCRFA for providing us the opportunity to continue translational research.”

Santanu Dasgupta, Ph.D., is using his BCRFA grant to investigate mitochondrial genome alterations in women suffering from triple negative breast cancer with a view to develop mitochondria-based early diagnosis and surveillance tools.

“Early detection of this lethal disease can save lives with available treatments,” Dasgupta said. “This grant will serve as the platform to generate clinically relevant data and open up avenues for comprehensive profiling of the mitochondrial genome in these women.”

Wednesday, December 15, 2021

USA College of Medicine establishes Black Men in White Coats affiliate chapter

Warren Law III, a first-year medical student, and Trentyn Shaw, a second-year medical student, are vice president and president, respectively, of the USA College of Medicine's affiliate chapter of Black Men in White Coats.
Only 2 percent of American doctors are Black men. Black men also have the lowest life expectancy of any major demographic group in the United States. 

This correlation comes as no surprise to Johnson Haynes Jr., M.D., assistant dean of diversity and inclusion and professor of internal medicine at the USA College of Medicine. 

He asks: “What if we had a medical workforce that actually reflected our patient population? What’s happening in society that more Black women are becoming doctors while Black men are stagnant?”

With the goal of increasing the number of Black men in the field of medicine, the USA College of Medicine has established an affiliate chapter of Black Men in White Coats. Mirroring the national organization’s mission, the local chapter seeks to accomplish this objective through exposure, inspiration and mentorship.

“Efforts such as this seek to dissect the systemic barriers preventing Black men from becoming medical doctors and the consequences on society at large,” said Haynes, who is the faculty sponsor for the new chapter. “Healthcare accounts for nearly 20 percent of the United States GDP, and a significant portion of that is driven by disparities in a system that lacks diverse physicians.” 

Second-year medical student Trentyn Shaw serves as the USA College of Medicine affiliate chapter’s president. “Representation: a single word that holds so much weight. Accomplishing one's dream is a scary task on its own, but doing it alone can make it that much harder,” he said. “Being an example for young Black men who aspire to be physicians is something crucial. Having representation shows that their dreams are capable of being accomplished, and we are living proof that it is.”

Shaw said his aim as president is to help lead and build the chapter into one that will serve and mentor the community, “ushering in a new and bigger wave of Black doctors.”

Warren Law III, a first-year medical student and the chapter’s vice president, echoed Shaw’s goals for the organization. “Becoming a Black male physician may be difficult to imagine for Black men, because it is highly likely that they have never seen one before. Put simply, it is difficult to ‘be’ what you can’t ‘see,’” he said. “What I hope to accomplish as vice president of BMWC, is to afford young learners the ability to see what they very well can become.” 

The USA College of Medicine’s affiliate chapter of Black Men in White Coats seeks members who are enrolled in, or have graduated from, professional school (medical, dental, veterinary or other health professions). 

Chapter meetings will be held at least once every three months with the purpose of supporting one another and to plan activities that focus on exposing Black youth (boys and young men) to medicine and providing them with mentorship. 

Through quarterly school visits, whether virtual or in-person, Haynes said the chapter plans to connect with local schools in partnership with the USA College of Medicine’s Office of Diversity and Inclusion. 

In March, the USA College of Medicine hosted a virtual screening of the documentary “Black Men In White Coats,” followed by a panel discussion led by Black male physicians and medical students. 

Contact Johnson Haynes Jr., M.D., at 251-341-4072 or jhaynes@health.southalabama.edu to join the USA College of Medicine’s affiliate chapter. 

Learn more about Black Men in White Coats

Scalici awarded 2021 Mayer Mitchell Award for Excellence in Cancer Research

Physician-scientist Jennifer M. Scalici, M.D., has been named the recipient of the 2021 Mayer Mitchell Award for Excellence in Cancer Research.

Scalici, chief of gynecologic oncology service at the USA Health Mitchell Cancer Institute and a professor of gynecologic oncology at the USA College of Medicine, directs MCI’s gynecologic oncology research.

Martin Heslin, M.D., director of the Mitchell Cancer
Institute, and Arlene Mitchell present the award to
Jennifer Scalici, M.D.
The $10,000 award is presented annually to a promising scientist at the Mitchell Cancer Institute upon the recommendation of a faculty committee. The award was established in 2009 by University of South Alabama Trustee Arlene Mitchell in memory of her late husband, Mayer Mitchell, a Mobile businessman, longtime USA trustee and formative figure in the establishment of the MCI.

Since joining the MCI in 2012, Scalici has focused her collaborative research on ovarian cancer carcinogenesis and chemo-prevention as well as the active DNA damage and repair mechanisms, and metabolic changes underlying gynecologic cancers.

Supported by grant funding from the U.S. Department of Defense, including a recent $450,000 award, she has led collaborations with Auburn University and the University of Virginia as she continues to examine the effectiveness of a novel compound, developed in-house at the MCI, for the prevention of ovarian cancer. Scalici also serves on numerous national committees focused on advancing the science and developing new clinical trials to advance the treatment of gynecologic cancers.

In addition, Scalici has built a clinical practice emphasizing evidence-based care and advanced surgical techniques for gynecologic malignancies. She served as site principal investigator for a clinical trial that brought fluorescent sentinel lymph node dissection in endometrial cancer to Mobile, a technique that has become integrated into the standard of care nationally.

“As a physician-scientist, Dr. Scalici fully understands the plight of women who are suffering from GYN cancers. She brings that unique understanding to the research lab, where she and her team continue to lead promising projects,” said John V. Marymont, M.D., M.B.A., vice president for medical affairs and dean of the USA College of Medicine. “She is very deserving of this honor.”

Scalici earned her medical degree from the University of Alabama at Birmingham. She completed a residency in obstetrics and gynecology at Northwestern University McGraw Medical Center in Chicago and a fellowship in gynecologic oncology at the University of Virginia Health System in Charlottesville, Va.

Meet a Med Student: Kayman Strickland-Beach

Kayman Strickland-Beach

Age: 23

Class of: 2024

Hometown: Homewood, Ala.

Undergrad/grad institution: University of South Alabama

Degrees earned: Bachelor of Science in biomedical sciences

Interests/hobbies: Traveling, entertaining my two huskies and coffee with friends.

Something unique about me: I am the first in my family to pursue a career as a physician.

Three of my favorite things: My husband, my kids (two foster kids and the newest addition born on Nov. 9) and my huskies.

What I enjoy most about being a student at the College of Medicine: The community of classmates and faculty is one of a kind. They truly support you as an individual and do all they can to help you thrive not only in your studies, but in all areas of your life.