The next Distinguished Scientist Seminar at the USA College of Medicine will be presented by Dr. Thomas Rothstein, lab director for the Feinstein-Immunology Laboratory at the Feinstein Institute for Medical Research in Manhasset, N.Y. His seminar, titled "Natural Antibody-Producing B1 Cells: From Mouse to Human and Back Again," will take place Sept. 23, 2010, at 4 p.m. in the Medical Sciences Building auditorium.
Dr. Rothstein’s laboratory research is directed toward elucidation of the function and role of B lymphocytes in health and disease. Over the years his research efforts have focused on a number of specific, interrelated areas. These areas currently include studies of B cell receptor signaling, B-1 cell function, B cell/T cell interactions, and apoptosis, and include a program project on molecular determinants of B-1 and B-2 cell responses.
Dr. Rothstein completed his internship and residency training in internal medicine at George Washington University Hospital and at Beth Israel Hospital/Harvard Medical School, respectively, interrupted by a research fellowship at the National Cancer Institute with Dr. Michael G. Mage.
Dr. Rothstein then completed a fellowship in hematology/oncology at Beth Israel Hospital/Harvard Medical School, the research portion of which was carried out at the Massachusetts Institute of Technology with Dr. Malcolm L. Gefter.
Subsequently, Dr. Rothstein joined the section of hematology in the department of medicine at the Boston University School of Medicine as an assistant professor. Over the next 24 years, Dr. Rothstein rose to the rank of professor of medicine and filled a number of roles including associate chief for research in the combined section of hematology/oncology, director of the research training in Blood Diseases and Resources Program, and director of the Immunobiology Unit.
In 2006, Dr. Rothstein was recruited to the Feinstein Institute for Medical Research as investigator and head of the Center for Oncology and Cell Biology. Over the years, Dr. Rothstein has served as chair of the cellular immunology study section of the Arthritis Foundation, as an ad hoc member of many NIH regular and special emphasis study sections, and as an associate editor of the Journal of Immunology. He is an elected member of the American Society for Clinical Investigation and the Association of American Physicians. Dr. Rothstein has mentored 17 graduate students and 24 postdoctoral fellows.
For more information on Dr. Rothstein's research, click here.
