Thursday, July 3, 2025

Faculty Affairs and Faculty Development thanks outgoing committee members, welcomes new members

As the Whiddon College of Medicine begins the 2025-2026 academic year, the Office of Faculty Affairs and Faculty Development would like to extend their gratitude to the five outgoing Faculty Committee on Appointments, Promotions, and Evaluations (FCAPE) members for their service and valuable contributions.

  • Bassam Bassam, M.D., Professor, Neurology
  • Brian Fouty, M.D., Professor, Internal Medicine
  • Leander Grimm Jr., M.D., Professor, Surgery
  • Charles Hartin Jr., M.D., Associate Professor, Surgery
  • Aishwarya Prakash, Ph.D., Associate Professor, Biochemistry and Molecular Biology

They also welcome three new members to FCAPE:

  • Rosemary Klecker, M.D., Associate Professor, Radiology
  • Nathan Polite, D.O., Associate Professor, Surgery
  • Shannon Tyler, M.D., Associate Professor, Internal Medicine

The Office of Faculty Affairs and Faculty Developments invites the Whiddon COM community to join them in welcoming the new committee members, and thanking all members, past and present, for their service and leadership. 

Mitchell Cancer Institute discovers new target in ovarian cancer cells, published in Scientific Reports, a Nature subsidiary

Kevin Lee, Ph.D., assistant professor of research for gynecologic oncology at MCI, is the corresponding author of the study.
By Jessica Jones

Scientists at the USA Health Mitchell Cancer Institute (MCI) have identified a vulnerability in ovarian cancer cells that could pave the way for new treatments. The research, recently published in Scientific Reports, uncovers the role of a little-known ion channel — called ASIC2 — in driving the growth of ovarian tumors.

The findings suggest that turning off this channel could help stop cancer cells from multiplying.

“This is an exciting step forward in understanding how ovarian cancer cells thrive in the acidic environments that tumors create,” said Kevin Lee, Ph.D., assistant professor of research for gynecologic oncology at MCI, and corresponding author of the study. “By targeting ASIC2, we may be able to disrupt a critical pathway that these cancer cells depend on to grow.”

Ovarian cancer is one of the most fatal cancers affecting women, often diagnosed at advanced stages. The study discovered that ASIC2, typically involved in sensing acidity, is unusually active in ovarian cancer cells. It appears to work together with another molecule, PDE10, to fuel a cancer-promoting signal called β-catenin.

When the research team blocked ASIC2 in lab models using a compound called Diminazene, cancer cells began to die.

This new connection between ASIC2, PDE10, and β-catenin signaling offers hope for developing drugs that cut off cancer growth at the source — by disrupting the internal chemistry of the tumor.

With this discovery, researchers plan to study how ASIC2 behaves in real tumor samples from patients, explore new drugs that specifically block ASIC2, and work toward translating these findings into clinical trials.

“Cancer research is often about connecting the dots, and this is a major connection,” Lee said. “Every new target gives us another chance to develop smarter, less toxic therapies — especially for diseases like ovarian cancer, where treatment options are limited.”

In addition to Lee, authors for the research include Tanvi Joshi, M.D., Sagar Chokshi, M.D., Mary Howard Singleton, and Elizabeth Catranis of the MCI; Annelise Wilhite, M.D., of Virginia Tech School of Medicine in Roanoke, Virginia; and Jennifer Scalici, M.D., of Emory University School of Medicine in Atlanta.

Learn more about the research study published in Scientific Reports on nature.com.

Nature is one of the world’s leading scientific journals, known for publishing high-impact, peer-reviewed research across the full range of science and medicine.

Wednesday, July 2, 2025

Moore to be recognized for innovation in research administration

Helen Moore
Helen Moore, manager of pre-award grant services at the Whiddon College of Medicine Research Administration and Development, has been selected for the 2025 Society of Research Administrators International (SRAI) Future of the Field Award.

The SRAI Future of the Field program aims to highlight the “up-and-comers” of research administration – those leading their peers and institutions, evolving the status quo, and innovating ways that advance the field. These are the individuals who will drive research administration forward in the decades to come.

As an award winner, Moore will be recognized at the 2025 SRAI Annual Meeting in San Antonio, Texas, in October.

The Society of Research Administrators International is the premier global research management society providing education, professional development and the latest comprehensive information about research management to professionals from more than 40 countries.

USA Health expands pulmonary care with addition of Odigwe

Chibuzo Clement Odigwe, M.D., MHA
Chibuzo Clement Odigwe, M.D., MHA, an accomplished pulmonologist and intensivist, recently joined USA Health.  

Born in Enugu, Nigeria, Odigwe brings a wealth of global experience, leading-edge clinical expertise, and a deep commitment to patient-centered care to his role.  

“I am guided by a 'patient-first' mindset, as I firmly believe in putting the patient first and center in all that we do and plan,” he said, “with our initial and ultimate goal being the maximization of patient well-being, healing and satisfaction.”  

Odigwe settled on a career in medicine relatively early in life. His path took him through training in Nigeria, the United Kingdom, and the United States. 

He completed his medical studies at the University of Calabar College of Medical Sciences and the University of Calabar Teaching Hospital in Nigeria. He completed his residency in internal medicine at the University of Illinois at Chicago/Presence St. Joseph Hospital, where he distinguished himself as Resident of the Year and received multiple accolades for teaching and humanitarian service. 

Odigwe then pursued a pulmonary and critical care fellowship at the University of South Carolina School of Medicine in Columbia, South Carolina, where he was awarded the Jason Spiers Award for Best Teaching Fellow. 

He was a recipient of the Aubrey Sheiham Public Health and Primary Care Scholarship, which is offered annually by The Cochrane Collaboration to health workers, consumers and researchers living in developing countries. Odigwe spent three months at the UK Cochrane Centre in Oxford, England, which was the first center dedicated to conducting systematic reviews of medical research, particularly randomized controlled trials. 

“During medical school and for the first few years after, I was drawn first to internal medicine and subsequently developed a strong interest in pulmonary and critical care medicine,” he said, “being attracted to its multidisciplinary nature and the opportunity it provides to leverage technology and physiology to improve patient outcomes.”  

Most recently, Odigwe practiced pulmonary and critical care medicine at Infirmary Health’s Diagnostic and Medical Clinic in Mobile, where he was one of the physicians in the hospital's inaugural intensivist program. 

He was involved in the internal medicine residency programs of both Thomas Hospital and Mobile Infirmary. At Mobile Infirmary, he also served as associate program director and faculty for the outpatient pulmonary medicine and ambulatory internal medicine programs. At Thomas Hospital, he served as a teaching faculty/preceptor for the pulmonary and critical care medicine program. Residents at Thomas Hospital awarded him The Crystal Apple Faculty Award for Excellence in Teaching in 2024. 

An assistant professor of internal medicine at the Whiddon College of Medicine, Odigwe is board-certified in internal medicine, pulmonary medicine, and critical care medicine by the American Board of Internal Medicine. He is a member of numerous professional societies including the American Thoracic Society, American College of Chest Physicians, Society of Critical Care Medicine, and Alliance for Academic Internal Medicine. 

Odigwe, who most recently completed a Master of Health Administration at Louisiana State University, has clinical interests in evidence-based medicine, medical education, and advanced pulmonary critical care. His work spans complex ICU cases, lung disease management, and the use of emerging technologies in respiratory care.  

Odigwe developed a strong interest in medical education and research in the academic setting early in his career. 

“As the saying goes, 'to teach is to learn twice,'” he said. “Practicing in an academic health system like USA Health will enable me to use state-of-the-art resources and facilities to provide my patients with world-class pulmonary care. It also enables me to participate in research and contribute toward the education of my younger colleagues, while also ensuring that I stay current and competent in my specialty.”    

Odigwe has experience treating acute respiratory distress syndrome, asthma, chronic obstructive pulmonary disease (COPD), sarcoidosis, non-cystic fibrosis bronchiectasis, interstitial lung disease, obstructive sleep apnea, pulmonary embolism and more.  

He is accepting new patients at the Mastin Internal Medicine clinic located at 2451 University Hospital Dr., Suite 102 in Mobile. To schedule an appointment, call 251-470-5890. 

Monday, June 30, 2025

USA Health residents win Doctors' Dilemma internal medicine competition 

Mohammad Alsit Alkhabbaz, M.D.; Hussein
Haidari, M.D.; and Matt Carr, M.D., with the trophy.
USA Health residents bested all other schools and programs in the Doctors’ Dilemma competition at the 2025 Alabama and Mississippi Chapters American College of Physicians (ACP) Scientific Meeting in Gulfport, Mississippi.   

First-year internal medicine resident Mohammad Alsit Alkhabbaz, M.D., second-year internal medicine resident Hussein Haidari, M.D., and second-year med-peds resident Matt Carr, M.D., represented USA Health, the academic health system for the University of South Alabama, on the winning team.  

Multiple programs throughout Alabama and Mississippi were represented, including University of Alabama at Birmingham and University of Mississippi Medical Center, in Doctors’ Dilemma, a medical knowledge competition that dates to the 1990s within ACP.   

“It was exciting to be able to participate in the Doctors’ Dilemma and represent the internal medicine residency,” Carr said. “The other programs all proved to be very knowledgeable and great competitors. We were fortunate to come out on top!”  

Teams of residents compete in a multi-round format, culminating in a championship round. The contest aims to foster resident and medical student learning and engagement in a friendly, competitive environment.  

USA Health’s team is now qualified to compete in the national competition in San Francisco at the 2026 ACP Internal Medicine Meeting.   

The American College of Physicians is a prestigious organization that recognizes specialists from the internal medicine field and strives to improve patient care. Founded in 1915, ACP is the largest medical specialty organization in the world with 161,000 members in more than 172 countries. It promotes the science and practice of medicine, and it supports internal medicine physicians in their quest for excellence.